Changes in version 0.1.3 Release Date: Unreleased Development Changelog: dev Added - New output_path = ":cache:" to store downloaded reference files in a dedicated cache folder. This is the new default behavior for download_reference(). - New get_isoformic_cache() function to retrieve the path to the cache folder. - New IsoformicExperiment class to encapsulate all workflow inputs with a disk-based backend and tidy interface. - New generics and methods for the IsoformicExperiment class: - col_data() - Retrieve Sample Metadata - row_data() - Retrieve Metadata for Transcripts in the Assay Data - annot_data() - Retrieve Aggregated Annotation Data (transcript-centric) - annot_data_transcripts() - Retrieve Transcript Annotation Data - annot_data_genes() - Retrieve Gene Annotation Data - annot_data_exons() - Retrieve Exon Annotation Data - tx_to_gene() - Retrieve Transcript to Gene Mapping from the Annotation - summarize_to_gene() - Summarize Transcript-level Expression to Gene-level - de_tx() - Retrieve Differential Expression Results for Transcripts - de_gene() - Retrieve Differential Expression Results for Genes - New interface for plot_log2fc() function to visualize log2 fold changes of transcripts within a gene. - New feature_column argument in plot_log2FC() to specify the column name in the DE results table that contains the feature names (e.g., gene or transcript names). - New file_type = "genome_fasta" option in download_reference() to download the genome FASTA file from GENCODE. Changed - Argument file_type in download_reference() is now "gff" by default. - Default GENCODE version in download_reference() is now "49" by default. - Argument output_path in download_reference() is now ":cache:". - Arguments DEG_DET_table and selected_genes in plot_log2FC() are now de_data and feature. Changes in version 0.1.2 Release Date: 2025-10-06 Development Changelog: 0.1.2 Added - New DuckDB based parse_annotation(). - New plot_genomic_context() function to visualize the genomic context of a gene with its transcripts. - New tx_type_palette() function to provide a default color palette for transcript types. Fixed - In make_tx_to_gene() output, wrong column name entrez_id replaced for tx_length. Changes in version 0.1.1 Release Date: 2024-06-18 Development Changelog: 0.1.1 Added - download_reference(): now supports organism = c("human", "mouse"), with organism = "human" being the default. - download_reference(): argument file_type = "gtf" is the default. - prepare_annotation(): Parse both GTF and GFF file formats into required annotation data. Fixed - prepare_profile_data(): accepts matrix and data.frame as input for the txi_transcript argument. Changes in version 0.1.0 Release Date: 2024-06-11 Development Changelog: 0.1.0 Added - Release of the initial workflow. Changes in version 0.0.1 Release Date: 2024-06-08 Development Changelog: 0.0.1 Added - Original workflow style code added.